Castor
Depends
Confidence: Medium
Buy if you run regulated clinical trials and can live with sales-led, per-study pricing; it is a legitimate, well-funded EDC.
New check
Comparison
Castor vs OpenClinica
Castor and OpenClinica both land on Depends.
OpenClinica
Depends
Confidence: Medium
Buy if you run regulated clinical trials and need a validated, compliance-heavy EDC (ISO 27001, SOC 2, FedRAMP program).
| Compare | ||
|---|---|---|
| Verdict | Depends | Depends |
| Best for | Clinical research teams | Sponsors and CROs running regulated trials |
| Who it's not for | Anyone not running clinical trials | Small labs needing a quick simple database |
| Privacy | No known public vulnerabilities found in the sources reviewed.10 | ISO 27001 certified, SOC 2 audited, MFA available . but two 2025 CVEs (XXE and a CVSS 8.8 path traversal) were disclosed. |
| Support quality | No support evidence in sources | No directional evidence found in sources |
| Public sentiment | Public review detail is thin in sources reviewed; G2 shows roughly 129 category reviews with users citing quick study builds.¹ | Reviews are middling . a 3.6/5 aggregate over 61 reviews . with buyers most often comparing it head-to-head against Castor, Medrio, and Medidata.13 |
| Biggest gotcha | Quote-based pricing means demos and negotiation before seeing any number⁷ | Self-hosted Community Edition means you own patching, upgrades, and regulatory validation.16 |
Pick Castor when
- Clinical research teams
- Biotech running regulated trials
- Academic and non-commercial studies
- Remote/decentralized trial research
When Castor is not a fit
- Anyone not running clinical trials
- Small teams needing a simple survey or contact list
- Buyers wanting transparent, self-serve pricing
- Non-regulated internal data collection
Pick OpenClinica when
- Sponsors and CROs running regulated trials
- Multi-centre academic studies
- Government-adjacent research needing FedRAMP
- Teams consolidating recruitment and EDC
When OpenClinica is not a fit
- Small labs needing a quick simple database
- Non-clinical surveys or registries
- Teams without capacity for study build and validation
- Buyers wanting self-serve transparent pricing
Sources
- Castor Reviews . G2g2.comreview
review
- Castor EDC . Capterracapterra.comreview
- Castor EDC . Software Advicesoftwareadvice.comreview
- Castor EDC Reviews . SoftwareWorldsoftwareworld.coreview
- Castor EDC vs GoFormz . Exafolexafol.comreview
- Castor Pricingcastoredc.comofficial
- When is my study free of charge? . Castor Helpdeskhelpdesk.castoredc.comofficial
- Security Statement . Castorcastoredc.comofficial
- Product security page . Castorcastoredc.comsecurity
- Castor Raises $45M Series Bcastoredc.comnews
- Castor secures $12 million . MobiHealthNewsmobihealthnews.comnews
- OpenClinica vs Castor (RFP.wiki)rfp.wikireview
- OpenClinica Reviews on GetAppgetapp.iereview
review