Express Scripts vs Upstart PBMs

Express Scripts

express-scripts.com

Analyzed October 14, 2026

Depends

Confidence: Medium

Large employers, insurers, and government programs buy Express Scripts as their pharmacy benefit manager.

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Upstart PBMs

modernhealthcare.com

Starting report…

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Depends Express Scripts Pending Upstart PBMs Independent comparison on Should I Use It

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Pick Express Scripts when

Large employers funding drug benefits
Health plans outsourcing pharmacy management
Medicare Part D plan sponsors
Government programs like TRICARE

When Express Scripts is not a fit

Individuals shopping on their own; enrollment runs through a plan
Small employers wanting transparent drug pricing
Independent pharmacies; Arkansas pharmacies sue this PBM
Anyone who picks their own PBM; members do not choose it

Sources

Express Scripts Reviews | Trustpilottrustpilot.com
review
Express Scripts Reviews & Complaints | ConsumerAffairsconsumeraffairs.com
review
Express Scripts Yelp Reviews (579)yelp.com
review
Express Scripts BBB Customer Reviewsbbb.org
review
Express Scripts is nothing but BULLSHIT!!!! : r/ChronicPainreddit.com
review
Express Scripts Fail : r/tricarereddit.com
review
Victims Of Express Scripts (Facebook group)facebook.com
review
FTC Secures Landmark Settlement with Express Scriptsftc.gov
news
Warren hearing on Express Scripts contract termswarren.senate.gov
news
Express Scripts targeted by Arkansas pharmacieshealthcaredive.com
news
Upstart PBMs chip away at market leadersmodernhealthcare.com
news
HIPAA Breach by Express Scripts Vendorhaynesboone.com
security
ESI mobile app credential stuffing member notificationattorneygeneral.delaware.gov
security
Notice Regarding TRICARE Beneficiary Datamilitaryrx.express-scripts.com
security
Express Scripts Frequently Asked Questionsexpress-scripts.com
official
2027 National Preferred Formulary Exclusionsexpress-scripts.com
official