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Comparison

MDPI vs PLOS

MDPI and PLOS both land on Depends.

MDPI

Depends
Confidence: Medium

Reasonable if you need fast, funded open-access publication and your institution accepts MDPI journals.

PLOS

Depends
Confidence: Medium

Good fit if your funder mandates open access, your work is sound-but-not-flashy, and you or your library can cover the ~$2,477 APC.

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MDPI versus PLOS
CompareMDPIPLOS
VerdictDependsDepends
Best forResearchers needing fast open-access publicationFunder-mandated open access
Who it's not forTenure-track researchers building prestige CVsResearchers needing fast turnaround . delays recur
PrivacyOne known incident: in August 2016 manuscript submission system logs were intercepted and copied; MDPI appears in breach databases.³One past data-breach notification on record; current scans report no threats; no dedicated security page found.
Support qualityMixed author reports; employees warn against companyRecurring complaints of long review delays
Public sentimentAcademic forum sentiment is split: users praise the fast turnaround but heavily criticize review rigor, fees, and reputation.Researchers on Reddit and ResearchGate repeatedly complain about long PLOS ONE review wait times, while accepting it as a reputable open-access fallback.
Biggest gotchaMany researchers report peers and hiring committees discount MDPI lines on a CV.⁷Published APC figures conflict: $1,931 vs $2,477 . verify the current fee before submitting16

Pick MDPI when

  • Researchers needing fast open-access publication
  • Authors with grant or institutional APC funding
  • Interdisciplinary work without an obvious journal home
  • Authors whose institutions already accept MDPI titles

When MDPI is not a fit

  • Tenure-track researchers building prestige CVs
  • Anyone whose institution discounts or flags MDPI journals
  • Authors who cannot pay an APC out of pocket
  • Fields where MDPI outlets carry stigma with peers and hiring committees

Pick PLOS when

  • Funder-mandated open access
  • Sound-but-unglamorous findings
  • Interdisciplinary work
  • Authors with APC funding or waivers

When PLOS is not a fit

  • Researchers needing fast turnaround . delays recur
  • Authors chasing prestige for hiring or grants
  • Unfunded authors facing the ~$2,477 APC
  • Anyone shopping for software . this is a publisher

Sources

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  12. MDPI . Wikipediaen.wikipedia.org
    news
  13. official
  14. official
  15. review
  16. review